Cystic Fibrosis in the Light of New Research

Book Preface

Cystic Fibrosis in the Light of New Research provides the latest research and clinical evidence that will be useful for clinicians, scientists and researchers to further their knowledge around this fascinating condition.

The authors have brought along their expertise and wealth of knowledge to produce this book, including the basic science that underlies the disease, the burden of bacterial and viral infections, immunologic aspects of CF, a variety of clinical measurements to predict prognosis and novel therapies including gene therapy.

This book will be invaluable and entertaining for anyone who is involved in the care of patients with cystic fibrosis.

Contents
Preface
1 Factors Affecting Prognosis and Prediction of Outcome in Cystic Fibrosis Lung Disease
2 Outcome Measures for Respiratory Physiotherapy in Cystic Fibrosis – Challenges and Advances
3 Oxidative Stress in Cystic Fibrosis
4 Cystic Fibrosis Related Diabetes
5 Cystic Fibrosis and Fertility
6 Medications to Enhance CFTR Activity
7 Respiratory Virus in Cystic Fibrosis – A Review of the Literature
8 An Overview of Infections in Cystic Fibrosis Airways and the Role of Environmental Conditions on Pseudomonas aeruginosa Biofilm Formation and Viability
9 New Molecular Diagnosis Approaches – From the Identification of Mutations to their Characterization
10 Emerging Roles of microRNAs in Cystic Fibrosis – From Pathogenesis to Development of New Therapies
11 New Research on the Importance of Cystic Fibrosis Transmembrane Conductance Regulator Function for Optimal Neutrophil Activity
12 Role of Non-coding RNAs in Cystic Fibrosis
13 Therapy for Cystic Fibrosis Caused by Nonsense Mutations
14 Integrating Viral and Nonviral Vectors for Cystic Fibrosis Gene Therapy in the Airways
15 In vivo Gene Correction of Cystic Fibrosis