CURRENT Medical Diagnosis and Treatment 2017

Book Preface

Current Medical Diagnosis & Treatment 201 7 (CMDT 201 7) is the 56th edition of this single-source reference for practitioners in both hospital and ambulatory settings. The book emphasizes the practical features of clinical diagnosis and patient management in all fields of internal medicine and in specialties of interest to primary care practitioners and to subspecialists who provide general care.

Our students have inspired us to look at issues of race and justice, which surely impact people’s health. We have therefore reviewed the content of our work to ensure that it contains the dignity and equality that every patient deserves.

INTENDED AUDIENCE FOR CMDT

House officers, medical students, and all other health professions students will find the descriptions of diagnostic and therapeutic modalities, with citations to the current literature, of everyday usefulness in patient care. Internists, family physicians, hospitalists, nurse practitioners, physicians’ assistants, and all primary care providers will appreciate CMDT as a ready reference and refresher text. Physicians in other specialties, pharmacists, and dentists will find the book a useful basic medical reference text. Nurses, nurse-practitioners, and physicians’ assistants will welcome the format and scope of the book as a means of referencing medical diagnosis and treatment. Patients and their family members who seek information about the nature of specific diseases and their diagnosis and treatment may also find this book to be a valuable resource.

NEW IN THIS EDITION OF CMDT

• Updated treatment recommendations for direct -acting oral anticoagulants ( dabigatran, rivaroxaban, apixaban, and edoxaban)
• New combination therapy (sacubitril plus valsartan) to improve clinical outcome in heart failure with reduced left ventricular ej ection fraction
• New information on Zika virus and infection caused by Elizabethkingia species
• Alternative, noninvasive diagnostic tests for the diagnosis of cirrhosis
• Diagnosis of Clostridium difficile by PCR tests, including newly recognized NAP 1 hypervirulent strains
• Treatment of recurrent C difficile infections with fidaxomicin
• Revised USPSTF recommendations for cardiovascular prevention methods
• New information on proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for hypercholesterolemia
• Latest antiviral regimens for chronic hepatitis C and treatment of autoimmune hepatitis
• New pneumococcal, meningococcal vaccines
• Update on influenza vaccines
• Update on MMR and HPV vaccines
• New FDA-approved medications for diabetes mellitus
• Update on anti-TNF and immunomodulatory therapies of inflammatory bowel disease
• New pharmacologic treatment for schizophrenia and bipolar disorder
• Updated recommendations regarding appendicitis
• New table summarizing 2 0 1 5 Revised Jones Criteria for rheumatic fever
• New table outlining European Society of Cardiology guidelines for defining and diagnosing pericarditis
• Latest information on treatment options for obesity
• Updated information on dilated cardiomyopathy and Tako-Tsubo cardiomyopathy
• Extensive revision of Disorders of Hemostasis, Thrombosis, & Anti thrombotic Therapy chapter
• Revised treatment recommendations for infective endocarditis
• Information on increasing deaths due to opioid overdose
• Update on predictors of acute coronary syndrome
• Updated and new treatment recommendations for HIV
• Latest treatment recommendations for latent tuberculosis in HIV-positive and HIV-negative patients
• Substantial revision of Nervous System Disorders chapter
• The combination of PET and CT imaging in preoperative staging and role of programmed cell-death – 1 (PD- 1 ) inhibitors (nivolumab and pembrolizumab) for non-small cell lung cancers
• Pharmacologic treatment for female hyposexual desire disorder
• Extensively revised section on Alcohol Use Disorder (Alcoholism)
• Updated treatment options for hepatitis C-associated renal disease and focal segmental glomerulosclerosis
• Revised treatment options for Cushing syndrome and hypercortisolism
• Latest revision of recommended adult immunization schedule from the Centers for Disease Control
• Two new online chapters: Lesbian & Bisexual Women’s Health and Transgender Health & Disease Prevention
• Expanded online Podiatry chapter